* Howard Says: July 29th, 2007 at 7:04 pm Dr. Kenny, How can you say the following: Concerta is not a prodrug, so the abuse potential is higher than it is for Vyvanse. What comparative trials do you base this on? What if I simply...
See more »
* Howard Says: July 29th, 2007 at 7:04 pm Dr. Kenny, How can you say the following: Concerta is not a prodrug, so the abuse potential is higher than it is for Vyvanse. What comparative trials do you base this on? What if I simply cleave Vyvanse? What if I double my 70mg to the PI noted level where liking was experienced? I don’t feel you are being very honest with visitors to your website. This all looks like it was taken from the Vyvanse website. What is the big deal about working between 4 and 6 pm. Don’t all the Long Acting products like Adderall XR and Concerta do that? How long does it take for Vyvanse to works since it is a prodrug? Why did they measure at 10am and not 8am? If it works until 6pm and was taken at 6am it should be working at 8. * Dr. Kenny Handelman Says: July 29th, 2007 at 11:24 pm Hi Howard, Thank you for your comments about Vyvanse. To answer you comment about ‘cleaving vyvanse’, allow me to explain more. Vyvanse is also known as ‘lisdexamfetamine’. The ‘lis’ refers to the proten ‘lysine’. The dexamfetamine - is the ADHD Medication. A ‘pro drug’ means that the medicine doesn’t work until it is split and becomes active. How is Vyvanse split into its two parts - the lysine (inert) and the dexamfetamine (the active medicine)? It can only happen after the medicine travels through the stomach and passes via the blood stream to the liver. So, although the other long acting medicines - i.e. Concerta, Adderall XR, Metadate CD, Ritalin LA, etc. are quite hard to abuse - the medicine within them is active right away. However, Vyvanse is not active unless you swallow it and it goes through the liver. So, if someone got creative and tried to extract the vyvanse so that they could snort it, or inject it (to get high), it will not do anything. But, if someone tried to extract the medicine from Concerta, Adderall XR, etc - they would get high. That is the difference. Hopefully this helps your understanding of Vyvanse. Dr. Kenny * krys Says: August 13th, 2007 at 12:50 am THIS IS MORE OF A QUESTION. MY 9 YEAR OLD SON IS 62 LBS. AND WAS JUST PUT ON VYVANSE 30 MG. TOMORROW WILL BE OUR FIRST TIME TAKING IT. I’M CONCERNED ABOUT THE POSSIBILITY OF INSOMNIA AND WHAT EFFECT DOES IT HAVE ON THE LIVER? HOW MUCH WEIGHT LOSE SHOULD WE EXPECT? I HAVE A HARD ENOUGH TIME GETTING HIM TO EAT. THE DR. TOOK HIM OFF OF ADDERRALL XR TO PLACE HIM ON THIS. * Allan Says: August 16th, 2007 at 1:34 am Hi, What would you recommend to treat ADHD with a comorbid mood disorder ? how is this med ? Allan * Dr. Kenny Handelman Says: August 16th, 2007 at 1:22 pm Krys, Thanks for your question about Vyvanse. I can comment on what you wrote, but of course you will have to speak to your doctor about specific treatment issues and recommendations. 1) Regarding the starting dose of Vyvanse - 30 mg is the right starting dose for a young child like yours. 2) Insomnia may be an issue with Vyvanse - though each individual will react differently - so it may not be an issue with your son. 3) Regarding Vyvanse’s effect on the liver- in the research done and the reports so far, there are no negative effects on the liver from Vyvanse. I know that because Vyvanse is converted from the ‘pro-drug’ to the active medicine in the liver, that some people may wonder if Vyvanse harms the liver. The short answer is - ‘no’. There is no evidence that Vyvanse harms the liver. 4) With respect to weight loss and vyvanse -this is a potential issue - and this relates to the fact that some people have a decrease in appetite with vyvanse (And all stimulant medicines, including adderall, ritalin, concerta, etc). Your doctor will need to monitor your son’s height and weight on any ADHD medication and adjust it accordingly - especially if your son has this side effect with Vyvanse. I hope these comments help. Dr. Kenny * Dr. Kenny Handelman Says: August 16th, 2007 at 1:29 pm Alan, You have asked about the treatment of ADHD with a comorbid mood disorder. There are two main mood disorders - major depression and bipolar disorder. The treatment of bipolar disorder and ADHD is very
See less »
Once it passes through the liver, a protein chain is taken off the medication and it becomes an active amphetamine. Therefore, the abuse potential for Vyvanse is much lower than most ADD/ADHD drugs.
Kaboodle will send you a newsletter and updates from your friends. You can unsubscribe at any time. Kaboodle does not sell or share your email address or personal information with anyone.
Kaboodle requires all users to provide their real date of birth as both a safety precaution and as a means
of preserving the integrity of the site. You will be able to hide this information from your profile if you wish.
Added by 2 people